PMC

Components of stress acting on the three faces of a cuboidal element. Solid lines indicate a force acting normal to face A, B, or C. Dashed lines indicate forces acting along the face, generating shear.

Schematic representation of the proposed triboelectric multilayers comprising self-powered mask. Inner three layers (from face side) are acting as TE filter and outer layer is the EL made with conducting mesh.

(A) Maximum force on the actin units decreases during ring assembly. Scale: pN. (B) Vectors of forces acting on nodes face toward the cell center at late assembly (10 min). Average arrow length is 3 pN.

Proposed structure-activity relationship for glycosides acting as PAMs at P2X7. (A) The chemical structure of ginsenoside-CK is shown with important groups highlighted. Glucose attachment (cyan) is critical for activity at P2X7. C-6 substitutions are not tolerated (yellow). (B) The chemical structure of ginsenoside-20(S)-Rg3 is demonstrated with positioning relative to the P2X7 binding mode (inverted). The C-3 glucose attachments (cyan) face up into the binding pocket. The C-20 hydroxyl group shows that stereochemistry and positioning are critical for activity at P2X7.